2nd Century Enterprise Systems (2CES) is a company-wide initiative to transform Boeing through process improvements, data management and technology enhancements. 2CES is about making our business better by enabling Boeing to streamline and simplify work, standardize processes and tools, meet future and expanding business needs, and unleash data and information to improve decision-making. A key aspect of this initiative involves integrating SAFe into the Boeing way of working all the way from the team level up through the portfolio. The 2CES program currently includes 16 ARTs, 3 Solution Trains, and a Super Solution Train, and a Portfolio with continued growth every Program Increment. Teams on the ARTs are developing business and technical process solutions, COTS configurations, integrations with legacy systems, as well as software development. Debbie Brey, a life-long Agile champion and the first internal SPCT, will describe the state of the transformation and the continued challenges of becoming a Lean-Agile enterprise.